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杨亦方 |
讲师 | |
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博士 | |||
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电 话: | |||
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传 真: | |||
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电子信箱:yangyifangcn@163.com | |||
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出生年月:1990.11 | |||
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研究方向:多肽化学 | |||
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毕业学校:内华达大学里诺分校 | |||
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职 务: | |||
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研究工作简介 | |||
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2019年5月毕业于美国内华达大学里诺分校化学专业,获得博士学位。于2019.08-2022.06在美国布法罗大学化学系从事博士后研究工作。2022年9月加入中国竞彩网应用化学系,承担了《材料成型方法概论》等课程的教学任务,目前主要从事多肽的结构与功能关系的研究工作。在ACS Chem. Biol.,Proc. Natl. Acad. Sci. U. S. A.,Bioorg. Chem.,Biochemistry等国际SCI期刊上发表学术论文5篇。 | |||
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代表性成果 1. Yang, Yifang; Lee, C.; Reddy, R. R.; Huang, D. J.; Zhong, W.; Nguyen-Tran, V. T. B.; Shen, W.; Lin, Q., Design of Potent and Proteolytically Stable Biaryl-Stapled GLP-1R/GIPR Peptide Dual Agonist. ACS Chem. Biol. 2022, 17(5), 1249-1258. 2. Yang, Yifang; Lin, J.; Harrington, A.; Cornilescu, G.; Lau, G. W.; Tal-Gan, Y., Designing Cyclic Competence Stimulating Peptide (CSP) Analogs with Pan-group Quorum-sensing Inhibition Activity in Streptococcus pneumoniae. Proc. Natl. Acad. Sci. U. S. A. 2020, 117(3), 1689-1699. 3. Yang, Yifang; Tal-Gan, Y., Exploring the Competence Stimulating Peptide (CSP) N-terminal Requirements for Effective ComD Receptor Activation in Group1 Streptococcus pneumoniae. Bioorg. Chem. 2019, 89, 102987. 4. Yang, Yifang; Cornilescu, G.; Tal-Gan, Y., Structural Characterization of Competence Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumoniae. Biochemistry. 2018, 57, 5359-5369. 5. Yang, Yifang; Koirala, B.; Sanchez, L. A.; Phillips, N. R.; Hamry, S. R.; Tal-Gan, Y., Structure-Activity Relationships of the Competence Stimulating Peptides (CSPs) in Streptococcus pneumoniae Reveal Motifs Critical for Intra-group and Cross-group ComD Receptor Activation. ACS Chem. Biol. 2017, 12 (4), 1141-1151 (Yang and Koirala are co-first authors). |