中国竞彩网

亢永强

讲师

博士

电    话：15735176557

传    真：

电子信箱：1090403716@qq.com

出生年月：1992.03.03

研究方向：靶向G-四链体DNA抗癌药物的研发

毕业学校：山西大学

职    务：

研究工作简介

2015年和2022年毕业于苏州大学和山西大学，分别获得学士和博士学位。目前主要从事靶向G-四链体DNA荧光配体的设计合成及抗癌活性研究。在国际SCI源期刊发表多篇论文，并授权两项发明专利。承担应用化学系《有机波谱化学》、《有机化学实验》和《大学物理》等课程的教学任务。

代表性成果

1 Kang, Y.; Wei, C., A stilbene derivative as dual-channel fluorescent probe for mitochondrial G-quadruplex DNA in living cells[J]. Spectrochim. Acta, Part A, 2022，278: 121316.

2 Kang, Y.; Wei, C., Crescent-shaped carbazole derivatives as light-up fluorescence probes for G-quadruplex dna and live cell imaging[J]. Chem. Biodivers., 2022, 19 (3): e202101030.

3 Kang, Y.; Wei, C., Highly selective turn-on red fluorescence probes for visualization of the G-quadruplexes DNA in living cells[J]. Spectrochim. Acta, Part A, 2022, 267: 120518.

4 Saran, R.; Piccolo, K. A.; He, Y.; Kang, Y.; Huang, P.-J. J.; Wei, C.; Chen, D.; Dieckmann, T.; Liu, J., Thioflavin T fluorescence and NMR spectroscopy suggesting a non-G-quadruplex structure for a sodium binding aptamer embedded in DNAzymes[J]. Can. J. Chem., 2021, 99 (11): 860-866.

5 Kang, Y.; Guo, Y.; Shi, H.; Ye, S.; Zhang, B., Synthesis and Characterization of Novel 1,4-Di(o-thioaryl)benzene Buta-1,3-diynes[J]. ChemistrySelect, 2018, 3 (25): 7054-7059.

6 Zhang, B.; Kang, Y.; Yang, L.; Chen, X., A S-arylation of 2-mercaptoazoles with diaryliodonium triflates under metal-free and base-free conditions[J]. ChemistrySelect, 2016, 1 (8): 1529-1532.

7 Zhang, B.; Kang, Y.; Shi, R., Synthesis of aromatic heterocyclic sulfide compounds[J]. Chin. J. Org. Chem., 2016, 36 (8): 1814-1823.

专利：

1 Zhang, B.; Kang, Y. Process for preparation of 1,3-butadiyne containing arylthio group and its application in molecular conductive wire. CN107011224A, 2017.

2 Zhang, B.; Tian, H.; Kang, Y. Method for preparation of benzimidazo[2,1-b]thiazole derivative. CN106866707A, 2017.